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Cake day: July 6th, 2023

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  • Quotes from the paper https://doi.org/10.1038/s41588-024-01921-5

    Over recent decades, the incidence of gout has steadily increased, largely due to lifestyle factors such as diet, obesity, and metabolic conditions

    The paper also indicates a global rise in gout going hand in hand with the rise in global metabolic dysfunction.

    Having looked at the paper, it good, really good… but the genetic factors are for a population in the current metabolic context (high carb diets, poor metabolic health). Some people can tolerate the modern food landscape really well, and those people don’t get gout (hence this paper). But just because people’s genetics are intolerant of the current food landscape, doesn’t mean they HAVE to get gout… It can be avoided, by cutting out carbs, fructose, and alcohol. So even if you have a genetic sensitivity that leads to gout, you can simply not eat the foods necessary for the condition.

    Here is the full paper: https://www.medrxiv.org/content/10.1101/2025.02.07.25321834v1.full.pdf




  • The CICO model isn’t helpful to most people.

    I strongly think we need to stop telling people about CICO. It’s a thermodynamic model, not a clinical model.

    It’s much better to use the insulin obesity model, it’s a clinical model - https://hackertalks.com/post/7617450

    Basically we are not Bomb Calorimeters. You can eat uranium with billions of calories and not gain weight. We are hormonal machines, which have amazing homeostasis feedback already built it, we have to eat appropriately so those systems actually work.

    An illustrative example: if you want to lose 1lbs in a month you have to eat 30 calories less per meal. Nobody is going to measure their calories that accurately, not to mention food labels can be 25% off the exact amount… which means every meal you are eating ±208 calories… (on a 2500kcal day diet).






  • jet@hackertalks.comtoAsk Lemmy@lemmy.worldWhat is your best diett hacks?
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    2 days ago

    Diet Hacks!

    Want to lower your LDL? (you shouldn’t want to do this)

    • Seed oils! (corn oil, canola oil, any veggie oil)

    Want to lower your uric acid? (you shouldn’t want to do this)

    • Allulose 20g a day reduces uric acid levels by 50% in some people in 6 weeks

    Want to dramatically improve your HBA1C before a blood draw?

    • Donate blood 2 weeks ahead of time (new blood cells created to replace the donated blood wont be glycated, lowering your HbA1C)

    Want to reduce your blood glucose levels dramatically? (do this)

    • Don’t eat any sugar or carbohydrates

    Food Dietary Advice:

    If your not in a rush, any whole food diet (no factory food), will work for most people

    If you want to reverse a problem, a ketogenic diet (no sugar, no carbohydrates) will help you claw your way back to normal in steady consistent steps

    If you have no time to waste and need to drop fat now… Go full carnivore

    Diet Tips:

    • Eat fat to lose fat
    • Eat two eggs before you allow yourself any snack
    • Eat butter as a snack - Not hungry enough to eat butter? Then your not actually hungry
    • Sometimes hunger is actually electrolyte cravings, take salt/potassium to reduce urges
    • A CGM (continuous glucose monitor) is an AMAZING tool, immediate food feedback, can have a accountability friend watch you and coach you. This is the best tool to stay on a good eating pattern.