I used to think like this… Nothing worked for me, so I said I don’t care.

Later I discovered how easy it is to be healthy, doesn’t even require much exercise, just a simple eating pattern. My health improved tremendously, and life is better.

Now I really care about my health, because I feel in control of my health.

Live long and die fast: healthy people don’t have long drawn out painful deaths, unhealthy people suffer for years and years before they kick the bucket. Healthspan is something under our control.

The Diabetes in SEA is a real puzzle. Rice has always been a staple of the local diet, so that can’t really account for the rise in type 2 diabetes.

If I had to speculate its a combination of both increased carbohydrate consumption (glucose spikes), process food (glucose spikes, inflammation), and the wide-spread adoption of industrial oils (inflammation, and attacks cholesterol). We know that most dietary problems come from mixing carbohydrates and fat (randle cycle inflammation)

If you are in the US then you might want to check out

• https://www.stelo.com/en-us/buy-stelo-one-time $100/month
• https://www.levels.com/ $40/month

I think glycemic index is only useful in the context of dosing insulin, not for gauging overall health of food. I find the carbohydrate-insulin model of health most compelling. The big difference is it’s the TIME of elevated blood sugar that is more important then the HEIGHT of the spike. Obviously reducing both is good, shorter time, lower spike, but if you have to focus on one, time has the biggest metabolic payoff.

haha, not sure if that was sarcasm (the internet makes us all skeptical, heh), but I’ve found CGMs to be a massively useful tool. Where I live I can order them from aliexpress for $20, and that gives me two weeks of biohacking protentional. I’ve found the best benefit by giving them to my friends so they can see what their bodies are doing, it’s been my sneaky way of convincing people to go low carb.

Great writeup

[CC @[email protected] ]

Just want to add if you ever want to debug what a sweetener is doing to your glucose or insulin there is a easy test you can do at home. Wear a CGM (Continuous glucose monitor), which are fairly inexpensive and OTC now. When your blood sugar is flat and stable, take a sample of the sweetener by itself, eat it, and watch the glucose response for the next hour. If it goes up, then there is glucose in it, if it goes down, then the sweetener causes a insulin response.

Currently there aren’t enough tools for small communities. It’s hard for a niche community to grow and flourish.

If you post something like ‘BBQ is delicious’, it becomes a open referendum for the entirety of Lemmy to tell you why everything you said is wrong. Everybody dog piles their own personal biases and issues. And that’s fine for a general discussion.

lemmy needs smaller community safe spaces so the conversations can grow by interested parties, that’s currently lacking. Like a subscriber only post, only seen by people who subscribe to a community. And then when it gets large enough, people can say I want this to be generally available. I think that would help a lot

Yeah, it’s good for high frequency communication because its more resilient to noise and capacitive interference.

LVDS is just a standard for pairwise low voltage differential signaling. You still need a protocol on top of that to talk to the video controller.

I hate April’s fools

why not make a community for your political discussions?

yeah, 100%. Not everybody gets gout, there is clearly a genetic profile that can develop gout… in the current metabolic context, and the modern diet.

People can’t control their genetics, they can control their metabolism, and their diet.

Fructose has uric acid as a byproduct of its metabolism [86]. Fructose induced hyperuricemia has a pathogenetic role in metabolic syndrome [78,87]. Higher insulin concentrations, associated with metabolic syndrome, reduce the renal excretion of uric acid [47,80,88]. Uric acid is an inhibitor of nitric oxide synthase, [78] which is the catalyst for nitric oxide, critical for circulatory and immune homeostasis.

Reducing circulating uric acid concentrations is one of the mechanistic components of improved blood pressure control that is observed with a reduction in fructose intake [89].

• Except from https://doi.org/10.1016/C2019-0-03604-7 section 7.3 Pathophysiology of gout

Here are the references

• 47 - https://doi.org/10.1016/j.semnephrol.2011.08.004
• 78 - https://doi.org/10.3899/jrheum.170806
• 80 - https://doi.org/10.1186/1758-5996-4-12
• 86 - https://doi.org/10.1152/physrev.00019.2009
• 87 - https://doi.org/10.1152/ajprenal.00140.2005
• 88 - https://doi.org/10.1001/jama.1991.03470210076036
• 89 - https://doi.org/10.1093/ajh/hpaa044

All of that is to say elevated uric acid is not the root of the problem, its a symptom of the core problem.

Quotes from the paper https://doi.org/10.1038/s41588-024-01921-5

Over recent decades, the incidence of gout has steadily increased, largely due to lifestyle factors such as diet, obesity, and metabolic conditions

The paper also indicates a global rise in gout going hand in hand with the rise in global metabolic dysfunction.

Having looked at the paper, it good, really good… but the genetic factors are for a population in the current metabolic context (high carb diets, poor metabolic health). Some people can tolerate the modern food landscape really well, and those people don’t get gout (hence this paper). But just because people’s genetics are intolerant of the current food landscape, doesn’t mean they HAVE to get gout… It can be avoided, by cutting out carbs, fructose, and alcohol. So even if you have a genetic sensitivity that leads to gout, you can simply not eat the foods necessary for the condition.

Here is the full paper: https://www.medrxiv.org/content/10.1101/2025.02.07.25321834v1.full.pdf

deleted by creator

That’s true, but the root cause of gout is carbs and fructose and alcohol. Lowering uric acid when gout is acute makes sense, but long term you want to get off the sugars and alcohols.

The CICO model isn’t helpful to most people.

I strongly think we need to stop telling people about CICO. It’s a thermodynamic model, not a clinical model.

It’s much better to use the insulin obesity model, it’s a clinical model - https://hackertalks.com/post/7617450

Basically we are not Bomb Calorimeters. You can eat uranium with billions of calories and not gain weight. We are hormonal machines, which have amazing homeostasis feedback already built it, we have to eat appropriately so those systems actually work.

An illustrative example: if you want to lose 1lbs in a month you have to eat 30 calories less per meal. Nobody is going to measure their calories that accurately, not to mention food labels can be 25% off the exact amount… which means every meal you are eating ±208 calories… (on a 2500kcal day diet).

National security letters and research… That’s why there is zero information, it’s all sealed.

That’s why the lawyer won’t say anything, they are not allowed to.

Wasn’t unheard of for PhD students at my university to get their research made secret while their PhD was in progress…created huge headaches for everyone, especially if they couldn’t get clearance to even see/finish their research.

Why can’t you degoogle a phone?

You can use GrapheneOS, or lineageOS… or a iphone, or a chinese phone…

Since its your home network you can block all network access except to signal for the phone.

use a house phone with only signal installed on it.

use a different phone user with only signal installed on it (you can use molly to share the same account on multiple phones)

yeah… i’ve noticed this too; Many people say I just appear out of thin air and startle them… that isn’t possible, I’m not stealthy… they just have zero situational awareness

Diet Hacks!

Want to lower your LDL? (you shouldn’t want to do this)

• Seed oils! (corn oil, canola oil, any veggie oil)

Want to lower your uric acid? (you shouldn’t want to do this)

• Allulose 20g a day reduces uric acid levels by 50% in some people in 6 weeks

Want to dramatically improve your HBA1C before a blood draw?

• Donate blood 2 weeks ahead of time (new blood cells created to replace the donated blood wont be glycated, lowering your HbA1C)

Want to reduce your blood glucose levels dramatically? (do this)

• Don’t eat any sugar or carbohydrates

Food Dietary Advice:

If your not in a rush, any whole food diet (no factory food), will work for most people

If you want to reverse a problem, a ketogenic diet (no sugar, no carbohydrates) will help you claw your way back to normal in steady consistent steps

If you have no time to waste and need to drop fat now… Go full carnivore

Diet Tips:

• Eat fat to lose fat
• Eat two eggs before you allow yourself any snack
• Eat butter as a snack - Not hungry enough to eat butter? Then your not actually hungry
• Sometimes hunger is actually electrolyte cravings, take salt/potassium to reduce urges
• A CGM (continuous glucose monitor) is an AMAZING tool, immediate food feedback, can have a accountability friend watch you and coach you. This is the best tool to stay on a good eating pattern.

It’s a interesting poster, but look at those error bars!

I wonder why the pre-study ratios of CVD and Cancer were much lower on the 8 hour eating window population?