Currently there aren’t enough tools for small communities. It’s hard for a niche community to grow and flourish.

If you post something like ‘BBQ is delicious’, it becomes a open referendum for the entirety of Lemmy to tell you why everything you said is wrong. Everybody dog piles their own personal biases and issues. And that’s fine for a general discussion.

lemmy needs smaller community safe spaces so the conversations can grow by interested parties, that’s currently lacking. Like a subscriber only post, only seen by people who subscribe to a community. And then when it gets large enough, people can say I want this to be generally available. I think that would help a lot

Yeah, it’s good for high frequency communication because its more resilient to noise and capacitive interference.

LVDS is just a standard for pairwise low voltage differential signaling. You still need a protocol on top of that to talk to the video controller.

I hate April’s fools

why not make a community for your political discussions?

yeah, 100%. Not everybody gets gout, there is clearly a genetic profile that can develop gout… in the current metabolic context, and the modern diet.

People can’t control their genetics, they can control their metabolism, and their diet.

Fructose has uric acid as a byproduct of its metabolism [86]. Fructose induced hyperuricemia has a pathogenetic role in metabolic syndrome [78,87]. Higher insulin concentrations, associated with metabolic syndrome, reduce the renal excretion of uric acid [47,80,88]. Uric acid is an inhibitor of nitric oxide synthase, [78] which is the catalyst for nitric oxide, critical for circulatory and immune homeostasis.

Reducing circulating uric acid concentrations is one of the mechanistic components of improved blood pressure control that is observed with a reduction in fructose intake [89].

• Except from https://doi.org/10.1016/C2019-0-03604-7 section 7.3 Pathophysiology of gout

Here are the references

• 47 - https://doi.org/10.1016/j.semnephrol.2011.08.004
• 78 - https://doi.org/10.3899/jrheum.170806
• 80 - https://doi.org/10.1186/1758-5996-4-12
• 86 - https://doi.org/10.1152/physrev.00019.2009
• 87 - https://doi.org/10.1152/ajprenal.00140.2005
• 88 - https://doi.org/10.1001/jama.1991.03470210076036
• 89 - https://doi.org/10.1093/ajh/hpaa044

All of that is to say elevated uric acid is not the root of the problem, its a symptom of the core problem.

Quotes from the paper https://doi.org/10.1038/s41588-024-01921-5

Over recent decades, the incidence of gout has steadily increased, largely due to lifestyle factors such as diet, obesity, and metabolic conditions

The paper also indicates a global rise in gout going hand in hand with the rise in global metabolic dysfunction.

Having looked at the paper, it good, really good… but the genetic factors are for a population in the current metabolic context (high carb diets, poor metabolic health). Some people can tolerate the modern food landscape really well, and those people don’t get gout (hence this paper). But just because people’s genetics are intolerant of the current food landscape, doesn’t mean they HAVE to get gout… It can be avoided, by cutting out carbs, fructose, and alcohol. So even if you have a genetic sensitivity that leads to gout, you can simply not eat the foods necessary for the condition.

Here is the full paper: https://www.medrxiv.org/content/10.1101/2025.02.07.25321834v1.full.pdf

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That’s true, but the root cause of gout is carbs and fructose and alcohol. Lowering uric acid when gout is acute makes sense, but long term you want to get off the sugars and alcohols.

The CICO model isn’t helpful to most people.

I strongly think we need to stop telling people about CICO. It’s a thermodynamic model, not a clinical model.

It’s much better to use the insulin obesity model, it’s a clinical model - https://hackertalks.com/post/7617450

Basically we are not Bomb Calorimeters. You can eat uranium with billions of calories and not gain weight. We are hormonal machines, which have amazing homeostasis feedback already built it, we have to eat appropriately so those systems actually work.

An illustrative example: if you want to lose 1lbs in a month you have to eat 30 calories less per meal. Nobody is going to measure their calories that accurately, not to mention food labels can be 25% off the exact amount… which means every meal you are eating ±208 calories… (on a 2500kcal day diet).

National security letters and research… That’s why there is zero information, it’s all sealed.

That’s why the lawyer won’t say anything, they are not allowed to.

Wasn’t unheard of for PhD students at my university to get their research made secret while their PhD was in progress…created huge headaches for everyone, especially if they couldn’t get clearance to even see/finish their research.

Why can’t you degoogle a phone?

You can use GrapheneOS, or lineageOS… or a iphone, or a chinese phone…

Since its your home network you can block all network access except to signal for the phone.

use a house phone with only signal installed on it.

use a different phone user with only signal installed on it (you can use molly to share the same account on multiple phones)

yeah… i’ve noticed this too; Many people say I just appear out of thin air and startle them… that isn’t possible, I’m not stealthy… they just have zero situational awareness

Diet Hacks!

Want to lower your LDL? (you shouldn’t want to do this)

• Seed oils! (corn oil, canola oil, any veggie oil)

Want to lower your uric acid? (you shouldn’t want to do this)

• Allulose 20g a day reduces uric acid levels by 50% in some people in 6 weeks

Want to dramatically improve your HBA1C before a blood draw?

• Donate blood 2 weeks ahead of time (new blood cells created to replace the donated blood wont be glycated, lowering your HbA1C)

Want to reduce your blood glucose levels dramatically? (do this)

• Don’t eat any sugar or carbohydrates

Food Dietary Advice:

If your not in a rush, any whole food diet (no factory food), will work for most people

If you want to reverse a problem, a ketogenic diet (no sugar, no carbohydrates) will help you claw your way back to normal in steady consistent steps

If you have no time to waste and need to drop fat now… Go full carnivore

Diet Tips:

• Eat fat to lose fat
• Eat two eggs before you allow yourself any snack
• Eat butter as a snack - Not hungry enough to eat butter? Then your not actually hungry
• Sometimes hunger is actually electrolyte cravings, take salt/potassium to reduce urges
• A CGM (continuous glucose monitor) is an AMAZING tool, immediate food feedback, can have a accountability friend watch you and coach you. This is the best tool to stay on a good eating pattern.

It’s a interesting poster, but look at those error bars!

I wonder why the pre-study ratios of CVD and Cancer were much lower on the 8 hour eating window population?

yeah, it sounds like it! you shouldn’t eat eggs!

This would be a cool gimmick

If you want to maximize paranoia, don’t forwarded end to end encrypted communication over unencrypted systems

Maximum paranoia.

The main profile should be very vanilla.

Use a secondary profile as your daily driver, play with the cross profile notifications

Use different logins for the main profile and secondary profiles.

First past the post, the winner take all voting system seen in most countries