Any program written for the .net clr ought to just run out of the box. There’s also an x64 to ARM translation layer that works much like Apple’s Rosetta. It will run the binary through a translation and execute that. I have one of the windows arm dev units. It works relatively well except on some games from my limited experience.
Or it is just corporate greed. Samsung would love to position something that is just okay into a premium price tier and not have to pay Intel. Sure they’re going to pay Qualcomm instead but you can bet that Qualcomm is giving some great introductory prices to their early partners.